What special precautions should I follow?

Before taking Diphenhydramine:

Please inform your doctor or pharmacist if you are allergic to it, or if you have any other allergies. Check the label for any inactive ingredients you may be allergic to.

Moreover, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., asthma, emphysema), glaucoma, heart problems, high blood pressure, liver disease, mental/mood changes, seizures, stomach problems (e.g., ulcers, obstruction), an overactive thyroid gland, or difficulty urinating (e.g., due to an enlarged prostate gland).

Additionally, let your doctor or pharmacist know if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., dimenhydrinate), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) for 2 weeks before, during, and 2 weeks after treatment with this medication. In some cases a serious, possibly fatal, drug interaction may occur.

Also tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antispasmodics (e.g., atropine, belladonna alkaloids), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), scopolamine, tricyclic antidepressants (e.g., amitriptyline).

This drug may make you dizzy or drowsy or cause blurred vision; use caution engaging in activities requiring alertness such as driving or using machinery. Limit the use of alcohol and certain other drowsiness-causing medications. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Additionally, the rapidly-dissolving and chewable preparations of this product may contain aspartame. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist regarding the safe use of this medicine.

Liquid preparations of this product may contain sugar and/or alcohol. Caution is advised if you have diabetes, alcohol dependence or liver disease. Ask your doctor or pharmacist about the safe use of this product.

Do not give this medication to a child younger than six years of age unless directed to do so by a doctor. Caution is advised when using this drug in children because they are more sensitive to the effects of antihistamines. This drug can often cause excitement in young children instead of drowsiness.

Caution is also advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness, drowsiness and low blood pressure.

This drug should be used only if clearly needed during pregnancy. Tell your doctor if you are pregnant before using this medication.

Moreover, this drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this medication. Consult your doctor before breast-feeding.

 

FDA Information

Why is this medication prescribed?

Other uses for this medicine

Dosage and using this medicine

What should I do if I forget a dose?

What side effects can this medication cause?

What storage conditions are needed for this medicine?

In case of an emergency/overdose

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